Results 91 to 100 of about 2,473,071 (281)
Persistent current in 2D topological superconductors
Scientific Reports, 2017 A junction between two boundaries of a topological superconductor (TSC), mediated by localized edge modes of Majorana fermions, is investigated. The tunneling of fermions across the junction depends on the magnetic flux.
Igor N. Karnaukhov
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Nonlinear coupling induced toroidal structure of edge localized modes [PDF]
, 2017 Edge localized modes (ELMs) are magnetohydrodynamic (MHD) instabilities that cause fast periodic relaxations of the strong edge pressure gradient in tokamak fusion plasmas.
Pamela, S. +39 more
core +1 more source
East European Journal of Physics, 2013 Recently the possibility of resonant excitation of pressure perturbation by external helical magnetic perturbations near the rotating plasma edge was shown taking into consideration the finite plasma conductivity.
Igor Pankratov +3 more
doaj
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Simulation of edge localized mode heat pulse using drift-kinetic ions and Boltzmann electrons
Nuclear Materials and Energy, 2019 This article reports on 1D+2V heat pulse propagation studies using the COGENT guiding center kinetic code. The model uses magnetized kinetic ions and a simple Boltzmann electron model.
I. Joseph, M.A. Dorf, M.R. Dorr
doaj +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
, 2018 Edge localized modes (ELMs) in high-confinement mode plasmas were completely suppressed in KSTAR by applying n = 1 nonaxisymmetric magnetic perturbations. Initially, the ELMs were intensified with a reduction of frequency, but completely suppressed later.
Lee, SG +12 more
core +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
The ballooning structure of small edge localized modes in AUG and TCV
, 2019 In future fusion devices the collisionality n e µ ne=T2 e at the pedestal top will be very low, n e;pedtop 0:06 [1], due to the expected high temperature.
Radovanovic, Lidija +14 more
core +4 more sources