Results 91 to 100 of about 2,944,639 (323)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
FEN-EDEBIYAT FAKÜLTESI DERGISİ
Fen-Edebiyat Fakültesi ...
Editör Editör
doaj
Crimean war on its 160th anniversary [PDF]
Akbulut, İlhan (Dogus Author)Kırım Savaşı, Osmanlı Padişahı Abdülmecid zamanında Osmanlı, İngiliz ve Fransız devletlerinin Rusya’ya karşı yaptıkları savaş olarak anılır. Sultan Abdülmecid’in Osmanlı İmparatorluğu’nu yeniden güçlü duruma getirmek amacıyla
Akbulut, İlhan
core
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Ponzi Finance from Mr. Ponzi to Mr. Madoff [PDF]
Ponzi finance is a type of financial fraud based on the principle of continuous fund rasing arising from the newcomers to the system. Ponzi scheme is inherently but necessarily tend to financial failure/bankruptcy.
Coskun, Yener
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Başlarken…İMGELEM Dergisi altı aylık hakemli beşeri bilimler yayınıdır ve birihtiyaca binaen doğmuştur. Türkiye yayın piyasasında birçok dergininhâlihazırda yayında olduğu bir gerçektir.
Editör Editör
doaj
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source

