Results 91 to 100 of about 2,944,639 (323)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

FEN-EDEBIYAT FAKÜLTESI DERGISİ

open access: yesSelçuk Üniversitesi Edebiyat Fakültesi Dergisi, 2016
Fen-Edebiyat Fakültesi ...
Editör Editör
doaj  

Crimean war on its 160th anniversary [PDF]

open access: yes, 2014
Akbulut, İlhan (Dogus Author)Kırım Savaşı, Osmanlı Padişahı Abdülmecid zamanında Osmanlı, İngiliz ve Fransız devletlerinin Rusya’ya karşı yaptıkları savaş olarak anılır. Sultan Abdülmecid’in Osmanlı İmparatorluğu’nu yeniden güçlü duruma getirmek amacıyla
Akbulut, İlhan
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Ponzi Finance from Mr. Ponzi to Mr. Madoff [PDF]

open access: yes
Ponzi finance is a type of financial fraud based on the principle of continuous fund rasing arising from the newcomers to the system. Ponzi scheme is inherently but necessarily tend to financial failure/bankruptcy.
Coskun, Yener
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Başlarken...

open access: yesİmgelem, 2017
Başlarken…İMGELEM Dergisi altı aylık hakemli beşeri bilimler yayınıdır ve birihtiyaca binaen doğmuştur. Türkiye yayın piyasasında birçok dergininhâlihazırda yayında olduğu bir gerçektir.
Editör Editör
doaj  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy