Results 21 to 30 of about 2,944,639 (323)
CRISPR-CasΦ from huge phages is a hypercompact genome editor
Science, 2020 Compact defense system in bacteriophages The CRISPR-Cas system, naturally found in many prokaryotes, is widely used for genome editing. CRISPR arrays in the bacterial genome, derived from the genome of invading viruses, are used to generate a CRISPR RNA ...
P. Pausch +9 more
semanticscholar +1 more source
Choice and constraint in migrant worker acculturation: towards a new approach [PDF]
, 2009 Following the unprecedented level of immigration into the UK in recent years, the issue features on a number of policy agendas, notably those around employment, where the impact of migrant workers and their relationships with indigenous workers have ...
Donnelly, Eddy +2 more
core +1 more source
Bilgi Dünyası, 2000 İnternet kaynaklarının makinaca anlaşılabilir olmamasından dolayı, kullanıcıların bilgi ihtiyacını karşılamada sorunlar yaşanmaktadır. Kaynakların yapısal olarak gösterilmemesi ve nasıl yorumlanması gerektiğinin ilgili kaynağa özgün çözümlerle hal ...
Baha Olgun, Hayri Sever
doaj +1 more source
Türk Kütüphaneciliği, 2017 This study investigates the issue of editorship and emphasizes the function and significance of editor within the scope of scientific publication. The editor is important on the mathematical objectivity and scientific validity of a scientific work and it
Yalçın Yalçınkaya
doaj +1 more source
Massively parallel assessment of human variants with base editor screens
Cell, 2020 Understanding the functional consequences of single-nucleotide variants is critical to uncovering the genetic underpinnings of diseases, but technologies to characterize variants are limiting.
Ruth E. Hanna +13 more
semanticscholar +1 more source
Who Did What: Editor Role Identification in Wikipedia
International Conference on Web and Social Media, 2021 Understanding the social roles played by contributors to online communities can facilitate the process of task routing. In this work, we develop new techniques to find roles in Wikipedia based on editors' low-level edit types and investigate how work
Diyi Yang +3 more
semanticscholar +1 more source
Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos
Science, 2019 Spotting off-targets from gene editing Unintended genomic modifications limit the potential therapeutic use of gene-editing tools. Available methods to find off-targets generally do not work in vivo or detect single-nucleotide changes.
Erwei Zuo +9 more
semanticscholar +1 more source
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
Nature Biotechnology, 2020 Existing adenine and cytosine base editors induce only a single type of modification, limiting the range of DNA alterations that can be created. Here we describe a CRISPR–Cas9-based synchronous programmable adenine and cytosine editor (SPACE) that can ...
Julian Grünewald +10 more
semanticscholar +1 more source
Nature BiotechnologyPrime editing enables precise installation of genomic substitutions, insertions and deletions in living systems. Efficient in vitro and in vivo delivery of prime editing components, however, remains a challenge.
Meirui An +8 more
semanticscholar +1 more source
Reviving second homes in tourism sector: the case of Muğla - Datça province [PDF]
, 2011 Türkiye son 20 yılda turizm alanında hızlı bir gelişme kaydetmiş, turist sayısı ve turizm geliri bakımından dünyada ilk on ülke içerisinde yer almayı başarmıştır.
Duman, Teoman, Kozak, Metin
core