Results 51 to 60 of about 2,236,140 (233)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Elektronik Yayıncılık, Bilimsel İletişim ve Kütüphaneler [PDF]
, 1997 This article deals with the electronic publishing and scientific communication and discusses, from various aspects, the impact of electronic publishing on libraries.
Tonta, Yaşar
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
YAZILI BASINDA FOTOĞRAF DIŞINDA KULLANILAN GÖRSEL ÖGELER: GRAFİKLER VE İLLUSTRASYONLAR
Selçuk İletişim, 2014 İlk önceleri görüntüsüz olarak yayınlanan gazetelerde, daha sonra elle çizilmiş resimler ve grafikler yer aldı. Fotoğrafın bulunması ve gazetelerde basılabilme olanaklarının geliştirilmesiyle birlikte yazısal bildirimler daha inandırıcı duruma geldi ...
Feyyaz Bodur
doaj
Revista Agrogeoambiental, 2009 Sumário de artigos com referências às páginas da edição impressa.
Editor Editor
doaj +1 more source
Tarihi kartlarda yaşayan İstanbul [PDF]
, 1996 Taha Toros Arşivi, Dosya No: 120-Köşkler, Kasırlar, Yalılar, Konaklarİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN ...
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2000 Taha Toros Arşivi, Dosya No: 34/A-Mina UrganUnutma İstanbul projesi İstanbul Kalkınma Ajansı'nın 2016 yılı "Yenilikçi ve Yaratıcı İstanbul Mali Destek Programı" kapsamında desteklenmiştir.
Ağaoğlu, Adalet +3 more
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