Results 111 to 120 of about 4,857,848 (301)

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

A Novel GmSIN1‐GmRNF1a‐GmCSN5a Module Determines Soybean Salt Tolerance and Yield Under Saline Soil Conditions

open access: yesAdvanced Science, EarlyView.
Soybean production is severely threatened by salt stress. This study reveals that the GmSIN1‐GmRNF1a‐GmCSN5a module enhances salt tolerance by stabilizing the GmSIN1 protein. GmRNF1a acts as an E3 ligase to ubiquitinate GmSIN1 for degradation, a process inhibited by GmCSN5a.
Jinlong Xu   +15 more
wiley   +1 more source

Programmable RNA N6,2´‐O‐Dimethyladenosine Editing

open access: yesAdvanced Science, EarlyView.
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li   +9 more
wiley   +1 more source

Plagio y ética en las publicaciones científicas

open access: yesAnales de Pediatría, 2019
Gonzalo Solís Sánchez   +4 more
doaj   +1 more source

For a Cosmopolitan Cinema – Editorial [PDF]

open access: yesAlphaville: Journal of Film and Screen Media, 2018
James Mulvey   +2 more
doaj  

The First Piece of the Pattern

open access: yesPatterns, 2020
Sarah Callaghan, Tessa Darbyshire
doaj   +1 more source

Editorial Editorial

open access: yesAnais Brasileiros de Dermatologia, 2004
Bernardo Gontijo   +2 more
openaire   +4 more sources

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