Results 131 to 140 of about 2,488,593 (306)
Prime editors (PEs) enhance gene editing precision but face repair mechanism limitations. DNA methylation (CpG sites) and de novo methyltransferases (DNMT3A/DNMT3B) boost PE efficiency. We developed an episomal PE system (epiPE) using EBNA1/oriP to sustain expression and methylation.
Xiaosong Han+15 more
wiley +1 more source
Dirac's wave mechanical theory of the electron and its field theoretical interpretation [PDF]
Editorial note: In this lecture, held at the meeting of the Berlin Physical Society, October 25, 1929, Lanczos discusses a nonlinear generalization of Proca's equation (derived from his ``fundamental equation'') such that the mass is multiplied by a scalar field function.
arxiv
Editorial Analytics: How News Media are Developing and Using Audience Data and Metrics
News organisations are increasingly embracing the use of analytics and metrics as part of editorial decision making, but what constitutes a sophisticated analytics strategy?
Federica Cherubini, R. Nielsen
semanticscholar +1 more source
The hydrogel incorporates Ag⁺‐loaded Preyssler‐type polyoxometalates (POMs) that release Ag⁺ ions in response to endogenous Na⁺ ions, ensuring controlled antibacterial activity. The spatially heterogeneous structure, created through dual‐channel fiber stacking and in situ cross‐linking, enhances structural integrity and promotes tissue regeneration ...
Zongtai Li+9 more
wiley +1 more source
Using the MOSTtechnology and whole‐liver Nissl staining method, a multi‐structural 3D pathological panorama of liver fibrosis is obtained. The damaged sinusoids, steatotic hepatocytes, and collagen deposition are all concentrated in pericentral areas.
Xiaochuan Zhang+13 more
wiley +1 more source
US employment exposure to domestic and foreign tariff changes under NAFTA
Abstract Literature examining the effects of changes in trade agreements and import competition on US employment and wages has focused primarily on non‐agricultural industries and changes in US import tariffs. We propose a method for measuring worker exposure to changes in agricultural tariffs using a newly developed county‐level dataset of employment ...
Diane E. Charlton+3 more
wiley +1 more source