Results 131 to 140 of about 6,162,273 (373)

Table of Contents, Volume 14, Number 1, 2016 [PDF]

open access: yes, 2016
Table of Contents for Volume 14, Issue Number ...
Editorial Board
core   +2 more sources

Genetic Manipulation of Mammalian Cells in Microphysiological Hydrogels

open access: yesAdvanced Science, EarlyView.
Supply channels for cells embedded in gels can be used for in situ genetic manipulation. Abstract Engineering functional 3D tissue constructs is essential for developing advanced organ‐like systems, with applications ranging from fundamental biological research to drug testing. The generation of complex multicellular structures requires the integration
Anna C. Jäkel   +2 more
wiley   +1 more source

Table of Contents, Volume 10, Number 2, 2012 [PDF]

open access: yes, 2012
Table of Contents for Volume Ten, Issue Number ...
Editorial Board
core   +1 more source

ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal‐Fetal Interface

open access: yesAdvanced Science, EarlyView.
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen   +7 more
wiley   +1 more source

Coronavirus infection (COVID-19) in Anales de Pediatría

open access: yesAnales de Pediatría (English Edition), 2020
Corsino Rey Galán   +4 more
doaj   +1 more source

In Memoriam of Andrew Webster

open access: yesNew Genetics and Society, 2022
Richard Tutton   +4 more
doaj   +1 more source

Engineering Adenine Deaminase TadA for Precise and PAM‐Flexible Point Mutagenesis and Gradient‐Tuning Endogenous Protein Design

open access: yesAdvanced Science, EarlyView.
Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun   +14 more
wiley   +1 more source

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