Results 71 to 80 of about 6,162,273 (373)
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang +16 more
wiley +1 more source
Diversity in the editorial boards of global health journals
BMJ Global Health, 2019 ### Summary box Diversity in global health workforce and leadership has received a lot of attention, particularly in terms of gender and representation of low/middle-income countries in global health institutions like the WHO.1–4 Representation of women
S. Bhaumik, J. Jagnoor
semanticscholar +1 more source
Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin +10 more
wiley +1 more source
Editorial (Spring) Board? Gender Composition in High-impact General Surgery Journals Over 20 Years
Annals of Surgery, 2019 Objective: To quantify gender composition of 10 high-impact general surgery journals, delineate how board composition has changed over time, and evaluate qualification metrics by gender.
C. A. Harris +6 more
semanticscholar +1 more source
Publication Bias and Editorial Statement on Negative Findings
Economic Journal, 2019 In February 2015, the editors of eight health economics journals sent out an editorial statement which aimed to reduce the extent of specification searching and reminds referees to accept studies that: ‘have potential scientific and publication merit ...
Cristina Blanco-Perez, Abel Brodeur
semanticscholar +1 more source
Practice Recommendations for Genetic Testing of Ataxias
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan +7 more
wiley +1 more source
Distribution of waves in the buildings and constructions having regular structure
MATEC Web of Conferences, 2017 In article settlement models of the buildings and constructions having periodic (regular) structure with a masses concentrated in nods are considered. Passing of waves in such systems is considered.
Mondrus Vladimir, Shutovskiy Stanislav
doaj +1 more source
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Annals of Clinical and Translational Neurology, EarlyView.Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski +13 more
wiley +1 more source