Results 111 to 120 of about 303,149 (294)

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Celebrating the Multiplicity of Social Work : An Invitation to a Translation Practice

Journal of Comparative Social Work, 2015
Editorial:Celebrating the Multiplicity of Social Work : An Invitation to a Translation ...
Yan Zhao
doaj  

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

Editorial 23(2): Special issue: Teaching and learning in higher education: Western Australia's TL Forum

, 2013
The Teaching and Learning Forum series of annual conferences has been conducted since 1992 by the five universities in Perth, Western Australia, namely Curtin University, Edith Cowan University, Murdoch University, The University of Notre Dame Australia,
McBeath, C., Nair, S., Phillips, R., Paull, M., Moore, C., Martin-Lynch, P., Etherington, S., Coffey, A., Atkinson, R., Morrison-Saunders, A.   +9 more
core  

Editorial: Language teacher education research - key trends, challenges, and questions

In this editorial, we introduce the Language Teacher Education Research (LTER) Journal as a new venue dedicated to researchers and practitioners in the field of language teacher education, providing a space to share, showcase, and advance their scholarly
Freeman, Donald, Kamali, Jaber, Bonny, Norton, Larsen-Freeman, Diane, Farrell, Thomas S. C.   +4 more
core   +1 more source

Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis

Advanced Science, EarlyView.
Blood‐based amino acid patterns measured by 19F NMR reveal hidden metabolic changes in colorectal cancer. By analyzing how these amino acids interact as a network, machine learning models identify patients at higher risk of recurrence and metastasis.
Ji‐Yeon Lee, Jumi Kim, Taehan Yoon, So Hyun Kwon, Su Chan Park, Dohyun Chun, Dohyeong Kim, Eun Jung Park, Hyunwoo Kim, Ji Min Lee   +9 more
wiley   +1 more source

2nd Evidence in Practice Award Open for Entries

, 2006
The 2nd Evidence in Practice Award is now open for entries. In approximately 750 words, can you describe a case study where your work has influenced clinical practice?
Editorial Team
core   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

Editorial for the 4th issue of “Communication and Language at Work – Bridging Theory and Practice”

, 2015
Editorial for the 4th issue of “Communication and Language at Work – Bridging Theory and ...
Kastberg, Peter
core  

Supporting implementation of Cochrane methods in complex communication reviews: resources developed and lessons learned for editorial practice and policy. [PDF]

Health Res Policy Syst, 2019
Ryan R, Hill S.
europepmc   +1 more source