Results 51 to 60 of about 1,424,891 (239)

Editor’s Note. Towards Blockchain Intelligence.

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2020
In this special issue, we want to gather some innovative applications that are currently pushing forward the research on Blockchain technologies. In particular, we are interested also in those applications that put the focus on the data, enabling new ...
Alejandro Baldominos Gómez   +1 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Editorial: Sweet sixteen [PDF]

open access: yes, 2018
This is the traditional triennial note used by the editors to give the readers of 4OR information on the state of the journal and its future. In the 3years that have passed since the last editorial note (Liberti et al.
Crama, Yves   +2 more
core   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Applied evolutionary anthropology: Darwinian approaches to contemporary world issues [PDF]

open access: yes, 2015
I appreciate the value of both evolutionary behavioural science and applied social research, and I see no better foundation for the latter than the former.
Price, ME
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

IJIMAI Editor's Note - Vol. 4 Issue 4

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2017
The research works presented in this issue are based on various topics of interest, among which are included: Radar Clutter, Radar Detectors Performance, Butterfly Optimization Algorithm, Artificial Bee Colony, Evolutionary strategy, Fractal Coding, User
Rubén González Crespo
doaj   +1 more source

Home - About - Disclaimer - Privacy