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IJIMAI Editor's Note - Vol. 4 Issue 1
International Journal of Interactive Multimedia and Artificial Intelligence, 2016 The research works presented in this issue are based on various topics of interest, among which are included: Pattern Recognition, Multimedia Information Retrieval, Knowledge extraction and knowledge mining, Data mining, Intelligent Systems & Artificial ...
Mohamed Bahaj
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
IJIMAI Editor's Note - Vol. 4 Issue 5
International Journal of Interactive Multimedia and Artificial Intelligence, 2017 Although Medicine has always been considered a Health Science, today it is not possible to obviate its relationship with other disciplines as Humanities and Basic Sciences.
Jose Luis Cebrián Carretero
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
IJIMAI Editor’s Note - Vol. 2 Issue 1
International Journal of Interactive Multimedia and Artificial Intelligence, 2013 This special issue “Artificial Intelligence and Social Application” includes extended versions of selected papers from Artificial Intelligence and Education area of the 13th edition of the Ibero-American Conference on Artificial Intelligence, held in ...
Elisa Boff, Juan Pavón Mestras
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Editorial: A New Chapter for IJIMAI.
International Journal of Interactive Multimedia and Artificial IntelligenceThe history of IJIMAI is a story of commitment, inclusion, and accessibility within the academic world. Since its founding, the journal has aimed to provide an open, free, and high-quality space for researchers and professionals in the fields of ...
Rubén González Crespo
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