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EDTA and Salts

International Journal of Toxicology, 2023
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1998, along with updated information regarding product types and concentrations of use and confirmed that EDTA and certain salts are safe as cosmetic ingredients in the practices of use and concentration as described in this report.
Priya, Cherian   +10 more
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Final Report on the Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, HEDTA, and Trisodium HEDTA

International Journal of Toxicology, 2002
EDTA (ethylenediamine tetraacetic acid) and its salts are substituted diamines. HEDTA (hydroxyethyl ethylenediamine triacetic acid) and its trisodium salt are substituted amines. These ingredients function as chelating agents in cosmetic formulations. The typical concentration of use of EDTA is less than 2%, with the other salts in current use at even
Rebecca S, Lanigan, Torill A, Yamarik
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EDTA-Dependent Lymphoagglutination

Laboratory Hematology, 2008
Lymphoagglutination is an extremely rare EDTA-dependent phenomenon and is far less frequent than neutrophil agglutination. We describe 6 new cases and briefly review the literature on lymphoagglutination.
Jean-François, Lesesve, Liliana, Vila
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EDTA-Induced Pseudothrombocytopenia

Southern Medical Journal, 1992
A 45-year-old man was admitted to the hospital because of unstable angina pectoris. During the wait for coronary artery bypass surgery, the platelet count gradually decreased from 154,000 to 20,000/mm3, without hemorrhagic manifestations. Medications were discontinued and surgery was postponed.
H, Mayan   +3 more
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EDTA-Dependent Leukoagglutination

American Journal of Clinical Pathology, 1990
Leukopenia (WBC 1.9 x 10(9)/L) was reported from an automated cell counter (TOA E-5,000, Symex) on a patient blood sample collected in ethylene diamine tetracetic acid (EDTA). Leukocyte aggregates of 30-50 cells were seen on the peripheral blood smear. Blood samples collected in heparin, citrate, and EDTA had white blood counts (WBC) of 8.1, 8.1, and 2.
C D, Hillyer, A N, Knopf, E M, Berkman
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Adsorption of EDTA and Metal–EDTA Complexes onto Goethite

Journal of Colloid and Interface Science, 1996
The adsorption characteristics of a variety of divalent and trivalent metal-EDTA complexes onto goethite (alpha-FeOOH) were examined in aqueous solution. Uncomplexed EDTA is adsorbed as a binuclear complex at low pH and as a mononuclear complex at high pH. Adsorption is ligand-like with a high extent of adsorption at low pH.
, Nowack, , Sigg
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Activation of rabbit kidney fructose diphosphatase by Mg-EDTA, Mn-EDTA and Co-EDTA complexes

Archives of Biochemistry and Biophysics, 1973
Abstract Purified rabbit kidney fructose diphosphatase requires both a free cation and a metal-chelate when assayed at pH 8 or below. In the presence Mg2+ or Mn2+, effective metal chelates were Mn(II)-EDTA, Mg(II)-EDTA, and Co(III)-EDTA. With Mg2+ as the cation the affinity of the enzyme for Mn(II)-EDTA or Mg(II)-EDTA was approximately the same, and ...
J S, Rosenberg   +3 more
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Biodegradation of EDTA

Applied Microbiology and Biotechnology, 1999
The chelating agent ethylenediaminetetraacetate (EDTA) is not degraded by conventional biological and physicochemical methods for the treatment of wastewater and the purification of drinking water. Of the measurable organic compounds it is the one present at the highest concentration in many surface and drinking waters.
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EDTA-assisted Pb phytoextraction

Chemosphere, 2009
Pb is one of the most widespread and metal pollutants in soil. It is generally concentrated in surface layers with only a minor portion of the total metal found in soil solution. Phytoextraction has been proposed as an inexpensive, sustainable, in situ plant-based technology that makes use of natural hyperaccumulators as well as high biomass producing ...
, Saifullah   +6 more
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Studies on EDTA complexes—II uranyl-EDTA system

Journal of Inorganic and Nuclear Chemistry, 1964
Abstract The uranium (VI)-EDTA system has been investigated spectrophotometrically. Evidence is presented for the formation of complexes, UO2YH-, (UO2)2Y, UO2(OH)YH2−, (UO2OH)2Y4− and their formation constants determined.
T.R. Bhat, M. Krishnamurthy
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