Results 71 to 80 of about 999,667 (302)
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Journal of Pharmacy and Bioallied SciencesPurpose: This study evaluates the effectiveness of different sequences of irrigation using sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA) on root canal disinfection, measured through bacterial reduction.
Saleh H. Alshudukhi +6 more
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
EDTA-extracted content of Cd, Cu, Pb and Zn (in mg kg of fraction-1) in the light fraction.
, 2019 EDTA-extracted content of Cd, Cu, Pb and Zn (in mg kg of fraction-1) in the light fraction.
Jolanta Komisarek (6755819) +1 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Microbial biomass dynamics after addition of EDTA into heavy metal contaminated soils
Plant, Soil and Environment, 2009 An incubation experiment with addition of EDTA and alfalfa into soils contaminated with heavy metal over 200 years was carried out in order to evaluate the EDTA effects on microbial properties. Alfalfa was added to soils together with EDTA to examine its
G. Mühlbachová
doaj +1 more source
, 2014 : The ESPN/ERA-EDTA Registry collects data on European children with end-stage renal disease receiving renal replacement therapy (RRT) who are listed on national and regional renal registries in Europe.
Chesnaye, Nicholas +20 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Speciation of EDTA in natural-waters: exchange kinetics of Fe-EDTA in river water
, 1995 In order to understand the speciation of EDTA, the exchange kinetics of Fe(III)-EDTA with other cations (Zn, Ca) are studied under the conditions of natural river water.
Sigg, Laura (author) +2 more
core +1 more source