Results 11 to 20 of about 4,282 (128)

Pubertal development and hypothalamic-pituitary-gonadal axis are altered in male mice lacking Mecp2. [PDF]

J Neuroendocrinol
Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Martín-Sánchez A, Jiménez-Díaz D, Esteve-Pérez R, Vasile-Tudorache A, Read JE, Howard SR, Agustín-Pavón C.   +6 more
europepmc   +2 more sources

Decoding the Heterogeneity of Diffuse Large B-Cell Lymphomas: A Comprehensive Genetic, Transcriptomic, and Phenotypic Profiling of B-Cell Lymphoma Cell Lines. [PDF]

Hematol Oncol
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent form of non‐Hodgkin lymphoma, exhibiting significant molecular and clinical heterogeneity. Advances in classification integrating phenotypic, genetic, and transcriptomic features have improved diagnosis and prognosis.
Pérez-Aguilera M, Pedrosa L, Gómez S, Salazar-Ortego S, Fernández-Miranda I, Muñoz-Viana R, Martín-Acosta P, Martín-Lunas BL, Jimeno R, Yanguas-Casás N, Horcajo B, Roncador G, Martínez-Climent JA, Ortega-Molina A, Sánchez-Beato M.   +14 more
europepmc   +2 more sources

Modeling Physical Activity Profiles in COPD Patients: A Basis Expansion Approach to Variable Domain Functional Regression Models. [PDF]

Biom J
ABSTRACT Physical activity plays an important role in the well‐being of patients with Chronic Obstructive Pulmonary Disease (COPD). The telEPOC program, developed at the Galdakao‐Usansolo University Hospital (Vizcaya, Spain), provided a telemonitoring data set resulting in a variable domain functional data set.
Hernández-Amaro P, Durbán M, Aguilera-Morillo MC, Gonzalez CE, Arostegui I.   +4 more
europepmc   +2 more sources

A novel integrated miRNA-donor age signature enables detection of cardiac allograft vasculopathy. [PDF]

Clin Transl Med
Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
González-Torrent I, Benedicto C, Delgado-Arija M, Pérez-Carrillo L, Giménez-Escamilla I, Tarazón E, Roselló-Lletí E.   +6 more
europepmc   +2 more sources

Fish Poxviruses on the Rise: Prospects for Aquatic Health. [PDF]

J Fish Dis
ABSTRACT Fish poxviruses are increasingly recognised as emerging pathogens of fish and should be considered in cases of unexplained gill or skin pathology. Carp edema virus (CEV), the causative agent of koi sleepy disease in common carp and koi (Cyprinus carpio), represents the first known example.
Adamek M, Matras M, Ojelade OC, Sano M, Gjessing MC, Korytar T, Falco A, Rakus K, Jung-Schroers V, Doszpoly A.   +9 more
europepmc   +2 more sources

Symbiotic Versatility in Action: Trebouxia Diversity Expands the Niche of the Lichen Xanthoria parietina. [PDF]

Environ Microbiol
Xanthoria parietina associates with an unexpectedly high diversity of Trebouxia phycobionts within clade A across the Mediterranean Basin. Climatic niche modelling reveals that differences in photobiont climatic preferences contribute to symbiont switching and help explain the broad ecological amplitude and geographic success of this widespread lichen.
Chiva S, Pazos T, Montero-Pau J, Moya P, Garrido-Benavent I, Barreno E, Muggia L.   +6 more
europepmc   +2 more sources

Generation of 3D reference dosimetric datasets towards adoption of model-based dose calculations for permanent implant prostate brachytherapy. [PDF]

Med Phys
Abstract Purpose This work aims to create and validate a comprehensive set of test cases and 3D reference dosimetric datasets for model‐based dose calculation algorithms (MBDCAs) in permanent implant prostate brachytherapy. These test cases address the limits of the standard TG‐43 formalism towards improving dose evaluations in prostate cancer ...
Akbari F, Peppa V, Ouellet S, Moghadam N, Oliver S, Gimenez-Alventosa V, Beaulieu L, Vijande J, Thomson RM.   +8 more
europepmc   +2 more sources

Advancing our understanding of valued living: An ecological momentary assessment of behavioral and experiential aspects of valued actions, well-being, and emotional distress. [PDF]

Appl Psychol Health Well Being
Abstract Although engaging in valued actions is often positively related to mental health, this relationship is not always consistent at the daily level, suggesting that how valued actions are experienced is also important. We examined three valued action aspects (extent of engagement, awareness of engaging in valued actions, and perceived effort) and ...
Sarrión P, Cebolla A, Santamaria-Rincon M, Llinares-Monllor C, Desdentado L, Baños R.   +5 more
europepmc   +2 more sources

A Multidomain Lifestyle Intervention Is Associated With Improved Functional Trajectories and Favorable Changes in Epigenetic Aging Markers in Frail Older Adults: A Randomized Controlled Trial. [PDF]

Aging Cell
In frail older adults, a 6‐month lifestyle intervention slowed epigenetic aging and improved functional outcomes, suggesting lifestyle strategies may delay biological aging and disability progression. ABSTRACT Frailty emerges as the intermediate stage preceding disability, but there is a gap in molecular signatures for early detection of subclinical ...
Olaso-Gonzalez G, Millan-Domingo F, Garcia-Fernandez L, Garcia-Tercero E, Cebrian M, Garcia-Dominguez C, Carbonell JA, Casabo-Valles G, Garcia-Gimenez JL, Tamayo-Torres E, Gambini J, Tarazona-Santabalbina FJ, Vina J, Gomez-Cabrera MC.   +13 more
europepmc   +2 more sources

Educación, empleo y cobertura médica en Argentina

Revista de Salud Pública, 2014
Este trabajo analiza la asociación entre disponibilidad de cobertura médica, empleo y educación. La interdependencia robusta de esas variables es el supuesto central de la estrategia de cobertura con fondos de enfermedad laborales para el acceso a la ...
Roberto Tafani, Rita Maldonado
doaj   +1 more source