Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Romantic Attachment and Cognitive-Emotional Regulation in Psychological Maladjustment
Romantic Attachment and Psychological Maladjustment: The study reveals that romantic attachment is a significant predictor of psychological maladjustment and depression.
Alicia Mena +3 more
doaj +1 more source
GRID Technologies => 'Education' = 'Distance Education'
This paper discusses the new possibilities that Grid technologies create in education, presents current learning paradigms and makes a prediction about the way in which Grid technologies may affect the future of education.
M. Xenos, B. Vassiliadis, A. Skodras
semanticscholar +1 more source
Teaching a distance higher education curriculum behind bars: challenges and opportunities [PDF]
The provision of education that is both effective and relevant to the needs of students within prison is challenging on a number of levels. The uniqueness of prison culture with a regime characterised by a focus on security measures such as lock-downs ...
Watts, Jacqueline H.
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Scale-Up Considerations of the Sundial Rotating Fresnel Solar Collector
In the frame of the ASTEP project two prototypes of the Sundial collector, together with a Phase Change Material Thermal Energy Storage, will be tested integrated with the industrial processes of two sites.
Mercedes Ibarra +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Exploring students’ experiences with authentic assessment in an online learning context
Authentic assessment brings a new dimension to assessment where learning and assessment are linked to genuine workplace environments. In this assessment, students apply knowledge and skills to solve real and felt workplace problems.
Cosmas Maphosa +2 more
doaj +1 more source
The use of WCAG and automatic tools by computer science students: a case study evaluating MOOC accessibility [PDF]
Web Content Accessibility Guidelines (WCAG) have been the de facto standard for Web accessibility evaluation for more than two decades and therefore have been introduced into legislation and university curriculum in Computer Science.
Francisco Iniesto, Covadonga Rodrigo
doaj +3 more sources

