The MoSMAR‐chip platform provides a high‐throughput and cost‐effective tool for identifying and characterizing antigen‐specific antibody‐secreting cells (ASCs) and memory B cells (MBCs) at the single‐cell level. The ASCs from coronavirus disease 2019 (COVID‐19) vaccine‐immunized mice were successfully analyzed, revealing diverse neutralizing antibodies
Tian Zhao+13 more
wiley +1 more source
Identifying the underlying challenges that face doctoral education in chemistry. [PDF]
Collini MA, Donkor B, Harshman J.
europepmc +1 more source
Enhanced arginine uptake is a critical feature of metabolic reprogramming in PTCL, characterized by elevated expression of the arginine transporter SLC3A2. SLC3A2‐mediated arginine uptake facilitates PTCL proliferation and survival by enhancing OXPHOS metabolism and inducing immune evasion.
Yimin Ren+13 more
wiley +1 more source
Embedding professional development within the curriculum of graduate programs: An impact survey from biomedical departments in a faculty of medicine. [PDF]
Miliotis H+5 more
europepmc +1 more source
Versatile and Robust Reservoir Computing with PWM‐Driven Heterogenous R–C Circuits
A robust physical reservoir computing (PRC) system using pulse‐width modulation (PWM)‐encoded R–C circuits is introduced. By enabling customizable nonlinearities and timescales, this system achieves state‐of‐the‐art accuracy in chaotic, multiscale, and multiclass tasks while maintaining stability across temperature variations and device batches.
Zelin Ma+9 more
wiley +1 more source
Potentialities and challenges of stricto sensu graduate studies in health: A qualitative meta-synthesis. [PDF]
Cassiano C+4 more
europepmc +1 more source
The Bioengineering of Microspheric Skin Organoids and Their Application in Drug Screening
A novel method for the preparation of uniform microspheric skin organoids via spinning bioreactors is developed. The organoid consists of a core‐shell structure to mimic the bilayered skin structure with the epidermis on the surface. For efficient drug screening, the organoid is equipped with a luciferase reporter to detect canonical Wnt signaling, and
Jundong Xie+5 more
wiley +1 more source
Clarification of public health pathways toward clinical careers: a pilot study describing a benchmark analysis project. [PDF]
Brown EA, Feliciano M, Martinez D.
europepmc +1 more source
Autonomous Self‐Evolving Research on Biomedical Data: The DREAM Paradigm
DREAM is a fully autonomous, self‐evolving biomedical research system capable of independently formulating scientific questions, performing analyses, and making new discoveries without human intervention. Validated in biomedical studies, DREAM significantly outperforms human scientists in research efficiency, accelerating scientific discovery and ...
Luojia Deng+3 more
wiley +1 more source
National Institute for Program Director Development: Providing Foundations and Connections for 30 Years. [PDF]
Woolever DR, Weaver K.
europepmc +1 more source