Results 121 to 130 of about 341,161 (169)

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model

open access: yesAdvanced Science, EarlyView.
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis   +7 more
wiley   +1 more source

Photonic Bayesian Neural Networks: Leveraging Programmable Noise for Robust and Uncertainty‐Aware Computing

open access: yesAdvanced Science, EarlyView.
This work introduces a novel photonic Bayesian neural network architecture that utilizes tunable photonic random number generators to independently control weight distribution parameters, significantly improving robustness, scalability, and accuracy while demonstrating practical applications in multimodal data processing and uncertainty‐aware computing.
Yangyang Zhuge   +9 more
wiley   +1 more source

Correlations in Magnetic Sub‐Domains as an Unconventional Phase Diagram for van der Waals Ferromagnets

open access: yesAdvanced Science, EarlyView.
An unconventional magnetic order is observed in exfoliated CrBr3 layers, characterized by vertically correlated planar magnetic sub‐domains. Magnetic force microscopy, ab initio calculations, and micromagnetic simulations indicate that these sub‐domains arise from stacking faults modifying interlayer exchange coupling.
Sergey Y. Grebenchuk   +9 more
wiley   +1 more source

Improving the Transition From Medical School to Residency in Obstetrics and Gynecology: Lessons Learned and Future Directions. [PDF]

open access: yesJ Grad Med Educ
Hammoud MM   +9 more
europepmc   +1 more source

Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress

open access: yesAdvanced Science, EarlyView.
Gestational environmental stress activates ER‐phagy by increasing placental Rtn3l mRNA N6‐methyladenosine modification, further inhibiting placental estradiol synthesis and contributing to fetal testicular dysplasia. This study demonstrates the early prevention and treatment of adult male infertility from the perspective of fetal‐derived diseases ...
Ye‐Xin Luo   +17 more
wiley   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

open access: yesAdvanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang   +11 more
wiley   +1 more source

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