Results 151 to 160 of about 400,775 (265)

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

open access: yesAdvanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Direct Growth of Transparent Boron Nitride Neutron Shielding Layer for Space Window

open access: yesAdvanced Science, EarlyView.
Direct growth of sp2‐sp3 hybridized BN (HBN) on quartz, enabled by an h‐BN buffer, produces transparent and stable films up to 80 µm thick with high transmittance and strong neutron shielding, making HBN a promising candidate for space windows in long‐term lunar missions.
Dobin Kim   +15 more
wiley   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

open access: yesAdvanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang   +10 more
wiley   +1 more source

Asymmetric Active Center Triggers Side‐On Photo‐Fenton‐Like Reaction Through Polar Charge Transfer and Self‐Adapting Sulfur Vacancies

open access: yesAdvanced Science, EarlyView.
The Cu‐Zn3In2S6 photocatalyst (Cu‐ZISV) with asymmetric Cu‐SV‐Zn sites was designed and synthesized to boost peroxymonosulfate (PMS) activation kinetics. The side‐on photo‐Fenton‐like reaction by the asymmetric Cu‐SV‐Zn site accelerated PMS activation and pollutant degradation, and the first‐order kinetic constant of Cu‐ZISV increased by 4.87 times ...
Jiaqi Hu   +7 more
wiley   +1 more source

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