Results 181 to 190 of about 400,775 (265)

Unsupervised Hierarchical Symbolic Regression for Interpretable Property Modeling in Complex Multi‐Variable Systems

open access: yesAdvanced Science, EarlyView.
UHSR translates complex chemical behavior into clear and explainable equations. Applied to thin‐layer chromatography, it automatically uncovers the mathematical rules linking a molecule's structure to its polarity. This approach matches the accuracy of advanced AI while providing interpretable results, earning greater trust from chemists. The method is
Siyu Lou   +4 more
wiley   +1 more source

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

open access: yesAdvanced Science, EarlyView.
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans   +8 more
wiley   +1 more source

Highly Sensitive and Temperature‐Insensitive Stretchable Strain Sensor with Microcrack‐Engineered Architecture

open access: yesAdvanced Science, EarlyView.
This study proposes a stretchable strain sensor that demonstrates a high gauge factor of 2.3 × 104 and excellent linearity (R2 = 0.98), while maintaining temperature insensitivity under applied strain. This performance is achieved through a microcrack architecture formed by stacking a brittle, low‐resistance material with a stretchable, high‐resistance
Yu Kato   +4 more
wiley   +1 more source

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

open access: yesAdvanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun   +13 more
wiley   +1 more source

Graduate Degree Holders in the U.S. Residency Match: Trends and Outcomes (2016-2024). [PDF]

open access: yesJ Med Educ Curric Dev
Barron DW   +4 more
europepmc   +1 more source

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