Results 111 to 120 of about 7,361,427 (296)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

O ensino de graduação na Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo ao longo dos seus 50 anos (1953-2003)

open access: yesRevista Latino-Americana de Enfermagem
Este artigo tem por objetivo descrever a trajetória do ensino de graduação desenvolvido na Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo (EERP-USP), ao longo dos seus 50 anos (1953-2003), trazendo subsídios para reflexões acerca do ...
Maria José Clapis   +5 more
doaj  

An Open Future for Higher Education [PDF]

open access: yes, 2010
As the world becomes more open, universities have the opportunity to embrace openness in how they carry out their operations, teaching, and research. Open educational resources can provide the catalyst for different forms of learning, linking formal and
Clow, Doug   +2 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Guidelines for Authors

open access: yesTuning Journal for Higher Education, 2014
Editorial Team Tuning Journal for Higher Education
doaj   +4 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

O ensino de enfermagem sobre HIV/ Aids sob a ótica da cidadania

open access: yesRevista Gaúcha de Enfermagem
O objetivo foi verificar a percepção de docentes de Enfermagem sobre sua responsabilidade na prática pedagógica em HIV/Aids e se valorizam a construção do conhecimento sobre a temática do HIV/Aids centrado nos parâmetros voltados à cidadania.
Simone de Oliveira Camillo   +2 more
doaj  

The Digital Revolution and Higher Education [PDF]

open access: yes, 2011
Presents survey findings about the views of college presidents and the public on the value of, prevalence of, and experience with online learning, as well as the role of the Internet and related technologies in education and prospects for future ...
Amanda Lenhart   +2 more
core  

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