Results 91 to 100 of about 3,018,363 (285)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Diversification of Higher Education
, 2020 During the 1980s, most European countries underwent substantial changes in their economic and educational systems. During the period it became clear that the discussions were going to be centered around the rapid changes being experienced by the higher ...
UNESCO European Centre for Higher Education
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Policy and Practice: A Development Education Review, 2006 Roland Tormey and Marie Kiely explore the capacity to use the process of learning to carry out ethnographic research as a vehicle for enabling students to learn, in an active way, the core thinking skills of development education, in higher education.
Roland Tormey, Marie Kiely
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Humidification and filtration performance study using Luffa packing in a dual stage system
Discover Applied SciencesCooling and humidification are commonly used in air conditioning systems, particularly for cooling applications. Evaporative cooling utilizes packing materials that retain water particles on their surface, increasing interaction with the incoming fluid ...
Shuaib Mohamed Akram +6 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Revista Română pentru Studii Baltice şi Nordice, 2011 While the Baltic Sea Region is considered to be a pioneer region in the development of regional integration and identity, the Black Sea Region is regarded to be a laggard in terms of regionali¬zation and region building.
Stefan Ewert
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
The state of Ohio higher education
, 2020 "January 14, 2020."A message from the chancellor -- A new governor -- A new student-focused state budget -- DeWine-Husted higher education budget priorities -- Ohio college opportunity grant -- Choose Ohio First scholarship -- Affordability and ...
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