Results 71 to 80 of about 17,195,294 (225)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The state of Ohio higher education

, 2020
"January 14, 2020."A message from the chancellor -- A new governor -- A new student-focused state budget -- DeWine-Husted higher education budget priorities -- Ohio college opportunity grant -- Choose Ohio First scholarship -- Affordability and ...

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Clinical Evaluation of Kinesio Taping Outcomes in Stage II Cellulite: A Pilot Study

Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija
Background. Cellulite is a common aesthetic condition linked to alterations in subcutaneous fat and dermal connective tissue, with possible impairment of microcirculation and lymphatic drainage. Kinesio taping (KT) is used in physiotherapy, but evidence
Laura Žalienė, Mercedes Šulcaitė-Vasiljeva, Simona Kasperavičiūtė, Jurgita Boltutienė, Simona Urbonienė, Daiva Stančaitytė , Gražina Šniepienė, Vitalija Gerikienė   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Proprietary credit transferability strategy plan : a report to the Governor, President and Minority Leader of the Senate, and Speaker and Minority Leader of the House of Representatives in Response to HB 49 and Ohio Revised Code 3333.166

, 2018
"December 31, 2018."; Includes bibliographical referencesIntroduction and charge of committee -- Principles for designing a strategy plan -- Key issues discussed -- Strategy plan -- ConclusionOhio Revised Code section 3333.166 charged the Chancellor of ...
Ohio. Department of Higher Education.
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Acknowledgement to 2015 reviewers

Canadian Journal of Higher Education, 2016
Canadian Journal of Higher Education
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Effect of carbon black from Ageratina adenophora and various other carbon anode plate additives on the performance of lead acid batteries

Chimica Techno Acta
The incorporation of carbon materials in batteries serves to enhance its performance by improving conductivity, achieving uniform active material distribution, increasing capacity, mitigating sulfation, extending cycle life, and considering potential ...
Subban Ravi, Baskaran Vignesh, Nagarajan Meimoorthy, Bharathamani Dhanus Kumar, Lakshmanan Sathishkumar, Nagarajan Mohankumar, Nagarajan Kannapiran   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Acknowledgement to Reviewers

Canadian Journal of Higher Education, 2015
Canadian Journal of Higher Education
doaj   +1 more source