Results 81 to 90 of about 17,195,294 (225)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Other title: Sharing courses/programs at Ohio's colleges and universities

open access: yes, 2017
"September 2017."Background -- Research -- Framework -- Recommended steps to implementing an institutional course/program collaboration -- ConclusionOhio Revised Code Section 3333.90 requires the Ohio Department of Higher Education (ODHE) to establish a ...
Ohio. Department of Higher Education
core  

Acknowledgement to reviewers

open access: yesCanadian Journal of Higher Education, 2014
Canadian Journal of Higher Education
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

AI Ethical Anxiety in Higher Education: Exploring Students' Cognitive Concerns and Behavioural Responses

open access: yesJournal of Digital Pedagogy
Growing concerns about the ethical issues of Artificial Intelligence technology in education have significantly influenced students' emotional and behavioural responses to its use, generating what this study refers to as "AI ethical anxiety".
Ahmed Mehdaoui
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Humidification and filtration performance study using Luffa packing in a dual stage system

open access: yesDiscover Applied Sciences
Cooling and humidification are commonly used in air conditioning systems, particularly for cooling applications. Evaporative cooling utilizes packing materials that retain water particles on their surface, increasing interaction with the incoming fluid ...
Shuaib Mohamed Akram   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Development education in higher education: Ethnographic research as a development education methodology

open access: yesPolicy and Practice: A Development Education Review, 2006
Roland Tormey and Marie Kiely explore the capacity to use the process of learning to carry out ethnographic research as a vehicle for enabling students to learn, in an active way, the core thinking skills of development education, in higher education.
Roland Tormey, Marie Kiely
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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