Results 61 to 70 of about 17,195,294 (225)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Diversity of structures for higher education [PDF]
, 2020 This book presents many of the papers that were delivered at a workshop on Universities, Colleges, and Others: Diversity of Structures for Higher Education, held at CEPES in 1993 in Bucharest, Romania. Among the compiled themes are as follows: 1) History,
UNESCO European Centre for Higher Education
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Higher Education Funding Study Council report
, 2006 Title from cover of PDF document (viewed July 3, 2006).; "May 2006."; Harvested from the web on 7/5/06[Topics:] Student focus/access/retention/affordability -- Operational and administrative efficiencies -- Workforce and economic development ...
Ohio. Higher Education Funding Study Council. +1 more
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South Carolina master plan for higher education [PDF]
, 1979 The South Carolina Commission on Higher Education published a master plan for higher education in response to a mandate by the General Assembly. The report provides recommendations, goals for post-secondary education, coordination and governance ...
South Carolina Commission on Higher Education
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Cogent Engineering, 2019 Drilling is a salient machining process employed in assembling the components and structures made from polymer composites. Influence of various drilling process parameters on the drilling process has been identified and controlled to maintain the ...
B. R. N. Murthy +6 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
The Condition of Higher Education in New Mexico 2005-2006 [PDF]
, 2019 The Condition of Higher Education in New Mexico 2005-2006 reports on data collected by the New Mexico Higher Education Department as part of its Data Editing and Reporting (DEAR) system.
New Mexico Higher Education Department
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SAGE Open, 2019 Cancer is the most dreaded and chronic disease with its treatment lasting almost lifelong with an uncertainty of cure. This not only adversely affects the quality of life among patients but also poses a psychosocial burden among family members ...
Bhaskaran Unnikrishnan +7 more
doaj +1 more source