Results 51 to 60 of about 17,195,294 (225)

Multi-ethnicity in higher education [PDF]

open access: yes, 2020
The multi-ethnic and pluricultural nature of European societies, indeed of world society, is (or should be) reflected both in the composition of the student cohorts and the staffs of higher education institutions. This same reality should also, of course,
UNESCO European Centre for Higher Education
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

2017 New Mexico Higher Education Department [PDF]

open access: yes, 2019
This report highlights how the New Mexico Higher Education Department is accomplishing the most sweeping and efficient articulation improvements in the history.
New Mexico Higher Education Department
core  

Comparative results of the state exit exams in the medical degree during five academia years

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: the state exit exams are the certification of the competence of the graduates. Analyzing the results obtained in this type of assessment is useful to detect deficiencies in the teaching-learning process.Objective: to describe, making a ...
Norkis Sánchez-Alonso   +4 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Diversification of Higher Education [PDF]

open access: yes, 2020
During the 1980s, most European countries underwent substantial changes in their economic and educational systems. During the period it became clear that the discussions were going to be centered around the rapid changes being experienced by the higher ...
UNESCO European Centre for Higher Education
core  

Logistic regression and prediction of low academic performance of students majoring in medicine

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: prediction of the academic performance of students can be useful for the institutions to devise strategies aimed at improving the development of the teaching-educational process.Objective: to determine the predictive capacity of some factors ...
José Ramón Martínez-Pérez   +4 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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