Results 171 to 180 of about 69,764 (234)

Serotonergic modulators in Alzheimer's disease: a hope in the hopeless condition

open access: yesChemistry &Biodiversity, Accepted Article.
Alzheimer disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Ali I. Al-Gareeb   +5 more
wiley   +1 more source

Acute Effects and Pharmacokinetics of LSD after Paroxetine or Placebo Pre‐Administration in a Randomized, Double‐Blind, Cross‐Over Phase I Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Psychedelics, such as psilocybin and lysergic acid diethylamide (LSD), are being investigated for the treatment of depressive and anxiety disorders, for which concomitant treatment with selective serotonin reuptake inhibitors (SSRIs) is prevalent.
Anna M. Becker   +12 more
wiley   +1 more source

Uncovering New Therapeutic Targets for Amyotrophic Lateral Sclerosis and Neurological Diseases Using Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost   +9 more
wiley   +1 more source

Antibiotic Use in Livestock Farming: A Driver of Multidrug Resistance? [PDF]

open access: yesMicroorganisms
Matheou A   +9 more
europepmc   +1 more source

Gel Electrophoretic Detection of Black Market ACE‐031

open access: yesDrug Testing and Analysis, EarlyView.
This article presents a study on black market ACE‐031 products and their detection by gel‐electrophoresis and Western blotting. Of the 14 tested products, only 12 contained an ACVR2B‐immunoreactive protein. However, mass spectrometry revealed that the products did not contain the ACVR2B‐Fc fusion protein ACE‐031 but instead the full‐length human ...
Christian Reichel   +3 more
wiley   +1 more source

Consensus‐Based Recommendations for Yoga as Adjunct Therapy in Eating Disorder Treatment: A Delphi Study

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study aimed to develop consensus‐based statements, combining the expertise of eating disorder (ED) clinicians and yoga instructors, on key considerations for applying yoga for individuals with anorexia nervosa, bulimia nervosa, and binge‐eating disorder.
Eleanor Trethewey   +6 more
wiley   +1 more source

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