Results 181 to 190 of about 250,842 (240)

Introducing Novel Surgical Clinical Correlations Into an Undergraduate Medical Anatomy Course

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Anatomy education is a hallmark of many preclinical medical school curricula, but students are often unable to identify the clinical relevance of anatomy and its applications. Vertical curricula that integrate clinical concepts into the preclinical basic science years and vice versa have been shown to benefit student learning and increase ...
Liam McLoughlin   +5 more
wiley   +1 more source

Chemical Characterization, Antioxidant, and Anticholinesterase Activities of Libidibia ferrea (Mart. Ex Tul.) L.P.Queiroz and In Silico Studies with the Acetylcholinesterase Enzyme

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Libidibia ferrea is used in many parts of Brazil for a variety of conditions, such as inflammation, respiratory disorders, muscle pain, and gastrointestinal problems. This study evaluated the chemistry and antioxidant and acetylcholinesterase (AChE) inhibitory activities of L. ferrea extracts. Hydroethanolic extracts of leaves (ELLF) and bark (
Lucas Soares Frota   +9 more
wiley   +1 more source

Linear and Two‐Dimensional Infrared Spectroscopy of the Multifunctional Vibrational Probe, 3‐(4‐Azidophenyl) Propiolonitrile. Deperturbing a Fermi Triad by Isotopic Substitution

open access: yesChemPhysChem, Volume 26, Issue 6, March 15, 2025.
Linear infrared spectroscopy combined with isotope labeling and density functional theory unravels the origin of a Fermi triad in a multifunctional vibrational chromophore. Ultrafast 2DIR‐spectroscopy reports directly on the dynamics and the intramolecular vibrational energy flow pathways in the isotopically deperturbed system. Abstract Infrared probes
Claudia Gräve   +4 more
wiley   +1 more source

Uncovering New Therapeutic Targets for Amyotrophic Lateral Sclerosis and Neurological Diseases Using Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost   +9 more
wiley   +1 more source

Gel Electrophoretic Detection of Black Market ACE‐031

open access: yesDrug Testing and Analysis, EarlyView.
This article presents a study on black market ACE‐031 products and their detection by gel‐electrophoresis and Western blotting. Of the 14 tested products, only 12 contained an ACVR2B‐immunoreactive protein. However, mass spectrometry revealed that the products did not contain the ACVR2B‐Fc fusion protein ACE‐031 but instead the full‐length human ...
Christian Reichel   +3 more
wiley   +1 more source

The effects of climate on bat morphology across space and time

open access: yesEcography, EarlyView.
According to Bergmann's and Allen's rules, climate change may drive morphological shifts in species, affecting body size and appendage length. These rules predict that species in colder climates tend to be larger and have shorter appendages to improve thermoregulation. Bats are thought to be sensitive to climate and are therefore expected to respond to
Laura Paltrinieri   +54 more
wiley   +1 more source

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