Results 181 to 190 of about 5,194,579 (284)
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
Mediators of educational differences in dementia risk later in life: evidence from the HUNT study. [PDF]
Mekonnen T+17 more
europepmc +1 more source
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli+15 more
wiley +1 more source
How Are We Preparing Australian and Aotearoa New Zealand Teachers to Be Health Promotors? Examining Physical Activity, Sleep and Sun Safety in Initial Teacher Education. [PDF]
Scott JJ+6 more
europepmc +1 more source
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
Sexual and reproductive health knowledge, attitudes and practices among adolescents in rural Thatta, Pakistan: a cross-sectional study. [PDF]
Inayat Ali A+3 more
europepmc +1 more source