Results 41 to 50 of about 17,004,984 (270)

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Pareceristas (2019)

open access: yesActa Scientiarum: Education, 2021
Pesquisadores que atuaram, no ano de 2019, como pareceristas ad hoc em processos de avaliação por pares de artigos submetidos à Revista Acta Scientiarum.Education.
Acta Scientiarum. Education
doaj  

Acknowledgement to Reviewers of Education Sciences in 2015

open access: yesEducation Sciences, 2016
The editors of Education Sciences would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...]
Education Sciences Editorial Office
doaj   +1 more source

Race, Class, And Gender In Boys\u27 Education: Repositioning Intersectionality Theory [PDF]

open access: yes, 2015
Boys\u27 identities are distinctly gendered, racialized, and classed across disparate social and cultural contexts. Related intersectional identity processes are associated with boys\u27 academic success.
Nelson, Joseph Derrick   +2 more
core   +2 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Pareceristas (2021)

open access: yesActa Scientiarum: Education, 2021
Pesquisadores que atuaram, no ano de 2021, como pareceristas ad hoc em processos de avaliação por pares de artigos submetidos à Revista Acta Scientiarum.Education.
Acta Scientiarum. Education
doaj  

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Acknowledgement to Reviewers of Education Sciences in 2019

open access: yesEducation Sciences, 2020
The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not [...]
Education Sciences Editorial Office
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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