Results 71 to 80 of about 18,232,304 (339)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The multiple mediation role of message-sending skills and the ability to deal with interference in listening and feedback [PDF]
Purpose – Listening is often considered the cornerstone of the communication process, with feedback being a crucial skill for effective management. The primary objective of this article was to investigate the relationship between managers’ listening ...
Mpumelelo Longweni +1 more
doaj +1 more source
THE USE OF INTERACTIVE MODELING IN THE TEACHING OF CHEMISTRY IN HIGHER EDUCATION INSTITUTIONS
O.V. Anichkina, O.Yu. Avdieieva
openalex +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Lingua + cucina: una ricetta che seduce gli studenti di ESL
Le trio cuisine, culture et apprentissage des langues est une recette qui fonctionne aussi dans le marché des échanges et des séjours linguistiques: c’est du moins le constat que fait ESL, organisateur de séjours linguistiques présent sur la scène ...
ESL education
doaj
Spring 2009, UNH Study Abroad: Explore the culture and charm of England through the UNH Cambridge Program [PDF]
Live in a private room at Cambridge University’s Gonville & Caius College, founded in the 1348 ~ Have your meals served in a gothic dining hall worthy of Harry Potter ~ Take two courses in British literature, writing or history, taught by British dons or
Center for International Education
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

