Results 71 to 80 of about 11,909,722 (288)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

American education [microform].

open access: yes, 1901
Title from cover."From kindergarten to college."Microfilm.Mode of access: Internet.Vols.
Boston University. School of Education.
core  

Acknowledgement to Reviewers of Education Sciences in 2013

open access: yesEducation Sciences, 2014
The editors of Education Sciences would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2013:
Education Sciences Editorial Office
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Sleep Disturbance in Adults with Type 2 Diabetes: Psychosocial Factors Across Anxiety Symptom Groups

open access: yesDiabetes, Metabolic Syndrome and Obesity
Dexia Li,1,* Wei Jin,2,* Leweihua Lin,2 Danhong Lin,2 Changchun Pu,1 Jiahuan Zhang,1 Yuheng Huang,3 Huibiao Quan,1 Jing Xiao31Department of Endocrinology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University ...
Li D   +8 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The multiple mediation role of message-sending skills and the ability to deal with interference in listening and feedback [PDF]

open access: yesEuropean Journal of Management Studies
Purpose – Listening is often considered the cornerstone of the communication process, with feedback being a crucial skill for effective management. The primary objective of this article was to investigate the relationship between managers’ listening ...
Mpumelelo Longweni   +1 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Lingua + cucina: una ricetta che seduce gli studenti di ESL

open access: yesBabylonia
Le trio cuisine, culture et apprentissage des langues est une recette qui fonctionne aussi dans le marché des échanges et des séjours linguistiques: c’est du moins le constat que fait ESL, organisateur de séjours linguistiques présent sur la scène ...
ESL education
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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