Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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American education [microform].
Title from cover."From kindergarten to college."Microfilm.Mode of access: Internet.Vols.
Boston University. School of Education.
core
Acknowledgement to Reviewers of Education Sciences in 2013
The editors of Education Sciences would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2013:
Education Sciences Editorial Office
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
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Sleep Disturbance in Adults with Type 2 Diabetes: Psychosocial Factors Across Anxiety Symptom Groups
Dexia Li,1,* Wei Jin,2,* Leweihua Lin,2 Danhong Lin,2 Changchun Pu,1 Jiahuan Zhang,1 Yuheng Huang,3 Huibiao Quan,1 Jing Xiao31Department of Endocrinology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University ...
Li D +8 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The multiple mediation role of message-sending skills and the ability to deal with interference in listening and feedback [PDF]
Purpose – Listening is often considered the cornerstone of the communication process, with feedback being a crucial skill for effective management. The primary objective of this article was to investigate the relationship between managers’ listening ...
Mpumelelo Longweni +1 more
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Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
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Lingua + cucina: una ricetta che seduce gli studenti di ESL
Le trio cuisine, culture et apprentissage des langues est une recette qui fonctionne aussi dans le marché des échanges et des séjours linguistiques: c’est du moins le constat que fait ESL, organisateur de séjours linguistiques présent sur la scène ...
ESL education
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
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