Results 91 to 100 of about 5,004,160 (315)

Egalité en classes mixtes en Education Physique: quels arrangements pour les enseignant-e-s ?

Formation et pratiques d’enseignement en question, 2013
Nous proposons un article franco-suisse dans lequel nous questionnons la valeur d’égalité comme principe fondateur de l’enseignement en classes mixtes en éducation physique et sportive. Les études évoquées ont été menées auprès d’enseignant.e.s et d’enseignant.e.s-stagiaires d’Education Physique et Sportive (EPS) à Lyon en France et à Genève en Suisse.
Sigolène Couchot-Schiex, Daniel Dariaz
openaire   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

LA CIUDAD COMO REFERENCIA PARA LA ENSEÑANZA DE LA GEOGRAFÍA EN UNA PERSPECTIVA SOCIOCONSTRUCTIVISTA

Didáctica Geográfica, 2014
Este texto aborda las demandas de la formación profesional para la enseñanza de la Geografía, teniendo en cuenta algunas características de la sociedad contemporánea. A partir de esas demandas, defiende la realización de una enseñanza de Geografía en una
doaj  

Formation initiale et modèles d’enseignement de nouveaux enseignants au collégial [PDF]

, 2014
formation des enseignants, modèles d’enseignement, pédagogies actives, pratiques ...
Le Coguiec, Eric, Leduc, Diane, Ménard, Louise   +2 more
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Theories and Models in Health Sciences Education – a Literature Review

Canadian Journal for the Scholarship of Teaching and Learning, 2019
Working within a scholarship of teaching and learning (SoTL) perspective requires a rigorous approach based on conceptual frameworks in order to build on previous developments.
Miriam Lacasse, Frederic Douville, Johanne Gagnon, Caroline Simard, Luc Côté   +4 more
doaj   +1 more source

Gestion, gouvernance et financement du numérique en éducation et en enseignement supérieur

Médiations & Médiatisations
Les domaines de l'éducation (Gravelle, Frigon et Monette, 2020) et de l'enseignement supérieur (Maltais, Ness, Jungblut et Rexe, 2023) sont en mutation mondiale, confrontés à des défis croissants.
France Gravelle, Martin Maltais
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Droit global et enseignement juridique au Japon: Premiers éléments d'une recherche (en droit) [PDF]

, 2013
Working Paper (30 pages); téléchargeable aussi sur Academia.euCe Working Paper présente les principaux éléments d'une recherche en cours ayant pour objet le droit global, saisi selon une approche pragmatique à partir d'une activité en particulier : l ...
Giraudou, Isabelle Juliette
core   +1 more source