Results 121 to 130 of about 5,004,160 (315)
, 2004 La société est plurielle. L'Etat lui-même est pluriel lorsqu'il emprunte des formes communautaires. Pourquoi l'école ne serait-elle pas, elle aussi plurielle ?
Delpérée, F. (Francis)
core
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
LAS COMPETENCIAS EN CIENCIAS SOCIALES EN EL TÍTULO DE MAESTRO DE EDUCACIÓN PRIMARIA
Didáctica Geográfica, 2012 RESUMEN: El presente artículo tiene como objetivo reflexionar sobre el estado de la cuestión y el análisis crítico de las competencias en ciencias sociales, para el nuevo Título de Grado de Maestro en Educación Primaria.
Clemente Herrero Fabregat +1 more
doaj
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
AkofenaRésumé: Cet article explore l'intégration croissante des plateformes en ligne dans l'enseignement universitaire en Algérie et leur impact sur la représentation interculturelle.
Bouthaina MAKHLOUF & Aziyadé KHADRAOUI
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
L’utilisation de modèles d’enseignement en stage par des futurs enseignants
Canadian Journal for New Scholars in Education, 2015 Cet article présente les résultats d'une étude exploratoire dressant un portrait des modèles d’enseignement utilisés dans un contexte de stage par 93 futurs enseignants de 4e année du baccalauréat en éducation préscolaire et en enseignement primaire.
Émilie Tremblay-Wragg +2 more
doaj
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source