Hydrophobic and Polarized Aromatic Residues Promote Internalization of Arg-Rich Cell-Penetrating Peptides through Ionpair-π Interactions. [PDF]
Khemaissa S +6 more
europepmc +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Anti-arthritic and endothelial protective effects of Derris scandens extract in adjuvant-induced arthritis in rats. [PDF]
Chaichamnong N +6 more
europepmc +1 more source
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Evaluation de l’enseignement par les étudiants : Exemple d’un atelier de simulation sur l’ECG. [PDF]
Mokaddem S +4 more
europepmc +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
U<sup>4+</sup> Speciation in Acidic Aqueous Solution: Insights from UV-Vis, EXAFS, XANES, and Quantum-Statistical Simulations. [PDF]
Raposo-Hernández G +4 more
europepmc +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Reducing Graft Failure and Reoperation After Anterior Cruciate Ligament Reconstruction in Professional Athletes Using a Systematic Surgical Approach: An Analysis of 342 Patients With a Mean Follow-up of 100 Months From the SANTI Study Group. [PDF]
Hopper GP +9 more
europepmc +1 more source

