Results 41 to 50 of about 495,907 (291)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Intercultural Exchanges in Internationalization of University: Study-Abroad Doctoral Students’ Lived experiences in Iran [PDF]

open access: yesTaḥqīqāt-i Farhangī-i Īrān, 2019
The present article describes and interprets the experiences of study-abroad doctoral students studying in Iran. The theoretical backgrounds behind the issue relate to "academic exchanges" and "doctoral studies" as important subdivisions of ...
Z. Niknam
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Les logiciels libres

open access: yesRevue Internationale d’Éducation de Sèvres, 1999
The « UNESCO-Netdays Project in Latin America and the Carribean » seeks to promote regional cooperative work through the use of free software and Internet in education. The Project gives a new basis for exchanges with European institutions.
Guillermo Lozano, Rodrigo Laurens
doaj   +1 more source

The eLIDA CAMEL: designed for learning by community [PDF]

open access: yes, 2008
This article, invited by the ALT Editor for the international ALT-N newsletter, reports on the work of the eLIDA CAMEL JISC-funded Design for Learning (D4L) competitively selected e-learning project.
Jameson, Jill
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Transactional Education and Transactional Educators: Fostering the Habit of “Using Intelligence Fully” [PDF]

open access: yes, 2003
This paper calls into question the assumptions implicit in many traditional theories of moral agency; namely, the assumption that moral agency requires the agent to be disinterested, disengaged, and psychically distant in order to be a good moral agent ...
Lowe, Barbara J.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Education Exchange [PDF]

open access: yesMRS Bulletin, 1996
Jonathan H. Fisher   +2 more
openaire   +3 more sources

THEORY AND PRACTICE OF ACADEMIC STUDENT EXCHANGES AND CO-OPERATION BETWEEN CHINESE AND RUSSIAN UNIVERSITIES

open access: yesRussian Studies in Culture and Society
The theory of academic exchanges emphasises the importance of international cooperation to improve the quality of education, stimulate innovation and promote cultural diversity.
Li Wenze
doaj   +1 more source

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