Results 61 to 70 of about 1,451,320 (258)

Integration of education for sustainability in the preschool curriculum: A comparative study between the two latest Swedish curricula

open access: yesJournal of Childhood, Education & Society, 2022
The aim of this study is to provide a content analysis of the new Swedish preschool curriculum in comparison with the previous preceding curriculum to investigate how sustainability and education for sustainability (EfS) have been described, and whether ...
Anders Ohlsson   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

ESD ‹in the Making›?

open access: yesMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung
The article explores potentials and limitations of educational making for education for sustainable development (ESD) based on a list of competencies proposed by ESD researchers to achieve transformational educational goals (Rieckmann 2021). It focuses
Anna-Lena Brown
doaj   +1 more source

Sustainable development as a meta-context for engineering education [PDF]

open access: yes, 2011
At the end of the first decade of the twenty-first century, there is unprecedented awareness of the need for a transformation in development, to meet the needs of the present while also preserving the ability of future generations to meet their own needs.
Desha, Cheryl   +2 more
core   +1 more source

Education for sustainable development and global citizenship. The challenge of the UN-decade [PDF]

open access: yes, 2005
This article informs about the achievements and conceptional insufficiencies of "education for sustainable development" on the politico-educational and school level in Great Britain.
Bourn, Douglas
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Beginning Scottish geography teachers' perceptions of education for sustainable development [PDF]

open access: yes, 2009
At the start of the 21st century the global pace of change and challenge continues unabated (Cullingford and Gunn, 2005). Increasingly individuals need to be equipped with the skills to manage and navigate uncertain futures (Irving, 1999).
Munro, R.K., Reid, Ashley
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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