Results 251 to 260 of about 70,031 (299)

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Germline pathogenic variant spectrum and prevalence among colorectal cancer patients undergoing multigene panel testing in Kazakhstan. [PDF]

Sci Rep
Baltayev N, Abdikerim S, Afonin G, Rasulov A, Zhunussova A, Kaidarova D, Zhunussova G.   +6 more
europepmc   +1 more source

Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids

Advanced Science, EarlyView.
A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang, Saewoon Shin, Seul‐Gi Lee, Kiup Kim, Yoojeong Kim, Jun Sun, Il‐Joo Cho, Joseph A. Gogos, Jong‐Chan Park, C‐Yoon Kim, Hyunjoo J. Lee   +10 more
wiley   +1 more source

Mismatch Between Physical and Psychological Outcomes at Return to Sport After ACL Reconstruction and the Association With Second ACL Injury Risk: A Cohort Study. [PDF]

Sports Health
Piussi R, Lindskog J, Högberg J, Hamrin Senorski R, Thomeé R, Buckthorpe M, Della Villa F, Samuelsson K, Hamrin Senorski E.   +8 more
europepmc   +1 more source

Knowledge, Attitude, and Perception of Medical Students Toward AI-Based Learning: A Cross-Sectional Study. [PDF]

Public Health Chall
Khan D, Dawood M, Ullah I, Thalib HI, Khan SY, Maheen F, Pereira M.   +6 more
europepmc   +1 more source

Individual and occupational correlates of work ability of Polish employees with visual impairments. [PDF]

Int J Occup Med Environ Health
Binder-Olibrowska KW, Jasiński AM, Wrzesińska MA.   +2 more
europepmc   +1 more source

Predicted positions and qualification mismatch for master of nursing graduates in Croatian hospitals: cross-sectional study. [PDF]

BMC Nurs
Vuksa A, Puljak L.
europepmc   +1 more source

Impact Assessment of Spatial Mismatch Between Grain Production and Consumption on Non-Point Source Pollution and Carbon Emissions from Grain Production in China. [PDF]

Foods
Yang H, Sieber S.
europepmc   +1 more source