Results 81 to 90 of about 8,671,176 (258)

Modèles de curricula et politiques curriculaires en Italie

Revue Internationale d’Éducation de Sèvres, 2011
This article describes the debate overthe curriculum in Italy over the last twenty years. Based on the change in design and practices ofthe curriculum in schools, the author offers a critical analysis of models, processes and control systems, and ...
Arduino Salatin
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Views from three continents : papers presented at the 1982 ICOMP International Conference on Management of Population Programmes

, 1983
Meeting: International Committee on the Management of Population Programmes, International Conference ...
Sattar, E., International Committee on the Management of Population Programmes   +1 more
core   +1 more source

The role of youth programmes in the transition from school to work [PDF]

The purpose of the study is to investigate how labour market regulation, modified by educational systems, affects the magnitude, composition and targeting of Youth Programmes.
Schröder, Lena
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Exploring Nursing and Medical Students’ Experiences of Handling Challenging Conversations: A Qualitative Focus Group Study

Advances in Medical Education and Practice
Germanus Natuhwera,1,2 Peter Ellis,3 Eve Namisango2,4,5 1Clinical & Administration Departments, Hospice Africa Uganda, Kampala, Uganda; 2Education Department, Institute of Hospice and Palliative Care in Africa, Kampala, Uganda; 3Independent Nursing ...
Natuhwera G, Ellis P, Namisango E
doaj  

L’enseignement obligatoire au Vietnam entre vouloir et pouvoir

Revue Internationale d’Éducation de Sèvres, 2016
Compulsory education is a reality that is experienced to varying degrees across the world. In Vietnam, such education, legally binding, was decreed for 5 years (primary cycle) after national independence and has gradually been implemented.
Trinh Van Minh, Trinh Thuy Duong
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The Utility And Recommendations Of Adapted Physical Activity In The Care Of People With Autism Spectrum Disorder In A Sports Environment

مجلة العلوم و التكنولوجية للنشاطات البدنية و الرياضية
This research aims to evaluate the impact of an adapted sports programme on children with autism spectrum disorder (ASD), through an experimental design based on a comparison between an experimental group that received the programme and a control group ...
ZENATI yassine, BENBERNOU Othmane, SEBBANE Mohamed   +2 more
doaj   +1 more source