Results 91 to 100 of about 233,294 (316)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Curriculum, entre modèle rationnel et irrationalité des sociétés
Revue Internationale d’Éducation de Sèvres, 2011 The author demonstrates the complementary nature of two different approaches to the concept of curricula. The article includes a table showing a rational model of the concept of a curriculum.
Philippe Jonnaert
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
COMPARATIVE STUDY OF ONGOING ADULT LEARNING IN PUBLIC SERVICES AND NON-PROFIT SECTOR (CASE STUDY)
Journal on Efficiency and Responsibility in Education and Science, 2012 The aim of this paper is to compare the diversity of lifelong learning in public administration and non-profit sector and determine whether after 2009 there have been financial changes in the field of lifelong education of economically active population ...
VARVAŽOVSKÁ, Pavla +1 more
doaj +1 more source
Revue Internationale d’Éducation de Sèvres, 2015 In Russia, history teaching today is confronting the traditional bipolar approach to national history, a confrontational vision of the world, the question of minorities and regional issues and the influence of administrative reforms on educational ...
Aleksei Kilin
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Revue Internationale d’Éducation de Sèvres, 2015 History is a long-established discipline in schools in France. Since its creation it has been placed under the aegis of politics, making it subject to frequent polemics about what should be taught, and how.
Patricia Legris
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
What is the impact of education programmes on children’s learning and school participation? [PDF]
, 2016 Most education programmes typically improve either school enrolment and attendance or learning outcomes. They rarely improve both. What works in most contexts Cash transfers had the largest and most consistent positive effects on increasing school ...
3ie. International Initiative for Impact Education
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source