Results 111 to 120 of about 8,295,675 (307)
Neuropsychiatric Disease and TreatmentDoreen Birungi Agasha,1,* Germanus Natuhwera,2,3,* Eve Namisango,4,5 Hanif Kasozi,6 Elizabeth Mbabazi,2 Stanley Wilson Acuda31Administration and Clinical Departments, Hospice Africa Uganda, Kampala, Uganda; 2Clinical Department, Hospice ...
Agasha DB +5 more
doaj
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
What is the impact of education programmes on children’s learning and school participation? [PDF]
, 2016 Most education programmes typically improve either school enrolment and attendance or learning outcomes. They rarely improve both. What works in most contexts Cash transfers had the largest and most consistent positive effects on increasing school ...
3ie. International Initiative for Impact Education
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Exploration of children's value patterns in relation to environmental education programmes. [PDF]
Front Psychol, 2023 Kelly T +4 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
An analytical understanding of how external sources inform and impact upon Somaliland’s national education and teacher education policy making processes [PDF]
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis investigates how external sources inform and impact Somaliland’s national teacher education policy making processes. In this research, external
Ahmed, Hassan Suleiman
core +2 more sources
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Captured voices in primary school art education. [PDF]
, 2007 Eisner (1972) articulated a long-standing orientation in art education as he described the triadic relationship between socio-centric, child-centred and discipline-centred approaches in art education praxis.
Price, Graham
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source