Results 131 to 140 of about 8,295,675 (307)

Social enterprises and NEETs: ethical and effective entrepreneurial skills programmes? [PDF]

open access: yes
If young people not in employment, education or training (NEET) participate in Entrepreneurial Skills Programmes (ESPs), delivered by social enterprises, there is an ethical responsibility to measure the outcomes of these programmes.
Hazenberg, Richard   +2 more
core  

How accessible is the STEM post 16 education provision, the pipeline to computing and engineering programmes? [PDF]

open access: yes, 2019
EngineeringUK (2018) are estimating UK has an engineering graduate-level shortfall of at least 22,000 per year, the Royal Academy is reporting that by 2024 the engineering shortfall in the UK will be 160,000.
Stallard, J.A.   +2 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

The development of university-level distance education in the context of Hong Kong's transition from a British colony to a special administrative region of China [PDF]

open access: yes
China resumed sovereignty over Hong Kong on I July, 1997. After being a British colony for more than 150 years, Hong Kong became a Special Administrative Region of China following the "one country, two systems" policy.
Leung, Wing-chung
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The EAA educational programme [PDF]

open access: yesInternational Journal of Andrology, 2005
openaire   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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