Results 141 to 150 of about 8,295,675 (307)

The Evolution of University Access Programmes in Ireland [PDF]

open access: yes
The aim of this report is to explore the historical development of third level access programmes in Ireland, that is, programmes aimed at improving access to third level education by the socio-economically disadvantaged.
Patricia O’ Reilly
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Mapping the AMR Infection Landscape in Bihar: Implications for Strengthening Policy and Clinical Practice

open access: yesAntibiotics
Background: Antimicrobial resistance (AMR) poses a significant threat to public health, especially in low- and middle-income countries (LMICs), where surveillance infrastructure is underdeveloped.
Vinay Modgil   +7 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

A pedagogical tool for science teacher education: Content Representation (CoRe) design [PDF]

open access: yes, 2010
The promotion of reflective practice amongst participants in teacher education programmes (e.g. Bain et al, 1999; Moon, 1999; Loughran & Corrigan, 1995; Shireen et al, 2003; Wallace & Louden, 2003) and the wider teaching community is widely championed ...
Hume, Anne Christine
core  

A Scoping Review on Quality Physical Education Programmes and Their Outcomes on Primary-Level Pupils. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Kingston Ú   +3 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

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