Results 91 to 100 of about 8,295,675 (307)

Le chardon et la rose

open access: yesRevue Internationale d’Éducation de Sèvres, 2016
This article provides an overview of the historical reasons and political and constitutional contexts that have led England and Scotland to adopt very different approaches to common education.
Alan Britton
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The Utility And Recommendations Of Adapted Physical Activity In The Care Of People With Autism Spectrum Disorder In A Sports Environment

open access: yesمجلة العلوم و التكنولوجية للنشاطات البدنية و الرياضية
This research aims to evaluate the impact of an adapted sports programme on children with autism spectrum disorder (ASD), through an experimental design based on a comparison between an experimental group that received the programme and a control group ...
ZENATI yassine   +2 more
doaj   +1 more source

Ce qu’il y a de commun, de différent et d’inégal dans le curriculum de l’éducation de base en Espagne

open access: yesRevue Internationale d’Éducation de Sèvres, 2016
Basic education is the cornerstone of an educational system with the curriculum at its core, as it reflects the meaning that a community intends to give to the universal schooling project.
Juan Carlos González Faraco   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Éducation gratuite et obligatoire : une étude sur le cas du Libéria

open access: yesRevue Internationale d’Éducation de Sèvres, 2016
This article examines what Liberian schools are teaching to students under the free, compulsory basic education policy. The authors conducted qualitative research among sixty stakeholders in education.
Charles Gbollie   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The roles of non-state providers in ten complementary education programmes

open access: yes, 2010
This contribution reviews ten case studies of complementary education programmes conducted by the USAID-funded Educational Quality Improvement Program 2. The state-non-state relationship in each case is explored to reveal the arrangements that permit non-
Joseph DeStefano   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The role of youth programmes in the transition from school to work [PDF]

open access: yes
The purpose of the study is to investigate how labour market regulation, modified by educational systems, affects the magnitude, composition and targeting of Youth Programmes.
Schröder, Lena
core  

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