Results 141 to 150 of about 15,152,515 (292)

Education responses to climate change and quality : two parts of the same agenda? [PDF]

open access: yes, 2010
Increasing attention to climate change and the current global economic crisis has underscored the need for approaches to education that equip and empower people of all ages to deal with uncertain environmental, economic and political futures.
Blum, Nicole   +3 more
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Quality Assurance Toolkit for Teacher Education Institutions (QATTEI): Guidelines

open access: yes, 2007
Quality Assurance in the education sector is one of the major initiatives of the Commonwealth of Learning (COL) in its Three-Year Plan for 2006-09. To achieve the outcome of enhanced quality at all levels of education, COL has been focusing its attention
Rama, K, Lakshmi, T K S
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

QUALITY OF EDUCATION IS THE QUALITY OF LIFE

open access: yes
The article provides a brief definition of education in the era of globalization, highlighting the role of education quality. It emphasizes that the ecological, socio-political, and economic problems and crises arising during globalization, as well as their solutions, are linked to the quality of education.
openaire   +2 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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