Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Effect of yogic education system and modern education system on sustained attention
Sustained attention is a vital function mediated by the right frontoparietal cortex. The Six Letter Cancellation Task (SLCT) measures sustained attention. Development of sustained attention in a yoga-based education system compared to a modern one is the theme of the present study.To compare the effectiveness of the Modern Education System (MES) and ...
H R Nagendra+2 more
openaire +4 more sources
A REVIEW OF THE PRESENT SYSTEM OF MEDICAL EDUCATION IN LONDON. [PDF]
W. Moxon
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Book Review: IV. Practical Theology: The Education of the Central Nervous System [PDF]
B. H. DeMent
openalex +1 more source
Graduate education in optics in Japan and the United States: impact of funding levels on educational structure [PDF]
We compare the optical science & engineering educational environments at two universities in two countries: Utsunomiya University in Japan, and the University of Arizona in the United States. Because the university education systems in the two countries are so different, we also explain how financial arrangements drive many of these differences and ...
arxiv
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Defining the Global Tendencies of Transformation of National Systems of Higher Education [PDF]
The article is aimed at generalizing and systematizing the general world tendencies of the development of higher education, as well as their adaptation to the introduction into national practice.
Grynevych Luidmyla V.
doaj
A National System of Education.Walter Scott Athearn [PDF]
J. A. Artman
openalex +1 more source