Results 111 to 120 of about 2,246,833 (341)

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Tailoring Education with GenAI: A New Horizon in Lesson Planning [PDF]

open access: yesarXiv
The advent of Generative AI (GenAI) in education presents a transformative approach to traditional teaching methodologies, which often overlook the diverse needs of individual students. This study introduces a GenAI tool, based on advanced natural language processing, designed as a digital assistant for educators, enabling the creation of customized ...
arxiv  

Integration of higher IT education in Ukraine in the global IT-educational space [PDF]

open access: yesarXiv, 2016
The article presents the results of a study of the current state of higher IT education system in Ukraine. The problems of reforming higher IT education system of Ukraine in accordance with the commitments made by Ukraine in connection with the ratification of the EU-Ukraine Agreement Law of Ukraine N 1678-VII of September 16, 2014. An indicator of the
arxiv  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Why are In-grade Retention Rates so High in Macao?

open access: yesCurrent Issues in Education, 2013
This paper seeks to address why in-grade retention rates are so high in Macao by examining the operation of its education system.  To this end, I shall draw on data from a qualitative research project on educational inequality in Macao, referring ...
Yi-Lee Wong
doaj  

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

Criterios para análisis comparativo de modelos y diseños educativos Critérios para a análi se comparativo de modelos e desenhos educacionais Criteria for a Comparative Analysis of Educational Models and Designs

open access: yesEducación y Educadores, 2008
Las elaboraciones teóricas acerca de modelos de enseñanza y diseños de la instrucción, han sido producciones analizadas por los didactas preocupados por investigar la acción pedagógica, y por los docentes que se encuentran comprometidos con la compleja ...
Lourdes Morán
doaj  

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