Results 141 to 150 of about 1,580,732 (315)
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo+11 more
wiley +1 more source
In response to Nobel prize in physiology or medicine by the Indian medical education system: How far and how close? [PDF]
Panigrahi SK, Bhattacharya S, Jahnavi G.
europepmc +1 more source
Attitudes toward grading systems used in medical education
Rosemary Bender
openalex +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
Exploring the social accountability challenges of nursing education system in Iran. [PDF]
Ezzati E+5 more
europepmc +1 more source
Estonian education system vs Spanish education system
When Estonia regained its independence from the Soviet regime, and as a consequence of the reform of its educational system, taking as a reference what they did in their neighbouring country Finland. Some analysts have defined it as the educational miracle in Estonia, being ratified for the results achieved in the PISA reports.
Ibáñez López-Quintana, Lidia+1 more
openaire +1 more source
Not only numerous academic and empirical studies recognise the educational factor as decisive on life and work trajectories, but also its integrating potential and role in the promotion of social cohesion are widely acknowledged. The diversity of current societies, the economic situation and the impact of neoliberal policies represent new challenges ...
Martínez Virto, Lucía+1 more
openaire +3 more sources
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim+11 more
wiley +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source