Results 61 to 70 of about 4,685,155 (297)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Higher Education Systems and Industrial Innovation [PDF]

open access: yes
This text discusses the approach adopted in a European research project concerning the relationships between science and industry. The analysis uses the notion of actors as vectors for the creation and diffusion of competences and knowledge throughout ...
Caroline Lanciano-Morandat   +2 more
core  

The hole in the wall: self organising systems in education [PDF]

open access: yes, 2010
Transcript of a keynote speech by Sugata Mitra at “Into something rich and strange” – making sense of the sea-change, the 2010 Association for Learning Technology Conference in Nottingham, England.
Mitra, Sugata
core  

Quality assurance in higher education: for whom and of what? [PDF]

open access: yes, 2009
Over the past two decades the quality assurance of higher education institutions has captured a growing interest as evidenced by the increasing number of national and transnational bodies engaged in this area.
Kimber, Megan, Pillay, Hitendra
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Models of schooling in the global age: the case of Japan

open access: yesRevue Internationale d’Éducation de Sèvres, 2014
In sum, in Japan today, we see a society that shares many educational trends with the rest of the world (e.g. globalization), while maintaining distinct features of its model of schooling.
Ryoko Tsuneyoshi
doaj   +1 more source

Education Systems, Growth and Welfare [PDF]

open access: yes
This paper focuses on the implications of Decentralized Education (DE) and Centralized Public Education (CPE) for growth and welfare in an overlapping generations model. Individuals choose learning time, consumption and human capital.
Nikos Benos
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The influence of science and technology on the foundation phase policies of the BRICS associate countries: A comparative study

open access: yesPerspectives in Education
The pervasive influence of science and technology globally necessitates thoroughly examining its impact on education systems as policymakers face the daunting task of recalibrating educational frameworks for contemporary professional requirements. These
Julia Correia , Deon Vos, Louw De Beer
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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