Results 41 to 50 of about 1,079,892 (268)

La quête des valeurs traditionnelles chinoises dans l’éducation contemporaine : mise à jour ou remise en cause ?

open access: yesRevue Internationale d’Éducation de Sèvres, 2021
This paper focuses on “obedience” as a traditional Chinese value. In the health sector, obedience was manifested in public cooperation with government control during the Covid-19 crisis, which enabled a restoration of public health security within months
Ora Kwo, Mingrui Yang
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of yogic education system and modern education system on memory

open access: yesInternational Journal of Yoga, 2009
Memory is more associated with the temporal cortex than other cortical areas. The two main components of memory are spatial and verbal which relate to right and left hemispheres of the brain, respectively. Many investigations have shown the beneficial effects of yoga on memory and temporal functions of the brain.
Rangan R, Nagendra H, Bhat G
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Inclusive Education In The Lebanese Educational System

open access: yesThe Journal of Studies in Language, Culture and Society, 2019
As a founding member of the United Nations, Lebanon aims to include its educational policy in the UN‟s Sustainable Development Goal (SDGs), in particular the fourth, which aims to ensure "inclusive and equitable quality education and promote lifelong learning opportunities for all".
Frangieh, Basma, Ramel, Serge
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Right to Education: Democratic Management end Public Policies in Time of Pandemic/Covid-19 in the State of Tocantins

open access: yesRevista Brasileira de Educação do Campo, 2020
The article aims to analyze democratic management as a principle of the right to education in the State of Tocantins, in times of Pandemic Covid-19. The discussion aims to elucidate public policies aimed at quality educational services in the public ...
Elaine Aires Nunes   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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