Results 131 to 140 of about 4,630,084 (309)
EncyclopediaEducational technologies refer to the set of digital tools, resources, applications, and methodologies used to facilitate the teaching–learning process. These technologies include software, online platforms, hardware devices (such as tablets, computers, and interactive whiteboards), and, if one wants to give special relevance, as it should be these ...
openaire +2 more sources
Digital Signal Processing Education: Technology and Tradition
, 2000 In this paper we discuss a DSP course presented to both University students and to participants on industrial short courses. The "traditional" DSP course will typically run over one to two semesters and usually cover the fundamental mathematics of z ...
Garcia-Alis, D +3 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Pre-service science teacher’s opinions on virtual labs and their use in biology
Research on Education and MediaThis study sought to investigate pre-service science teachers’ opinions about using virtual laboratories and virtual laboratories for biology. The study group of the research consisted of four pre-service science teachers (two girls and two boys) who had
Koca Asiye Bilge, Kizilay Esra
doaj +1 more source
Chichester College of Arts, Science and Technology (FEFC inspection report; 72/95 and 43/99) [PDF]
, 1999 Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1994-95 (72/95), and 1998-99 (43/99). The FEFC has a legal duty to make sure further education in England is properly assessed.
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The Cathedral of Being: Re-enchantment and the Writings of the Popes [PDF]
, 2015 A rarely discussed issue that bears upon the topic of education is that which takes seriously the relationship between medium and message; how is the content of what is taught shaped by the way in which it is taught?
Tilley, Robert
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source