Results 131 to 140 of about 4,758,137 (365)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Constructing and development of the psycho-computing traits scale: a psychometric analysis of computer users and students in the field of computer science

Cogent Social Sciences
Psycho-computing refers to the study of the interaction between humans and computers, with the aim of understanding how people use computer applications in line with their needs and improving their experience.
Shoeb Saleh, Rommel AlAli
doaj   +1 more source

Meeting the demands of industry: A study on identifying and teaching emerging technologies in Engineering Education

, 2023
Bronwyn Swartz, Sweta Patnaik
openalex   +2 more sources

Editorial: BILETA special issue: Technology and Legal Education [PDF]

, 2014
Fragmentation and convergence are two discoursal lenses that have been used to view changes that have taken place in the domains of legal services,the legal profession, regulation and legal education. While they may appear orthogon al, the relationships
Maharg, P
core   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Blockchain in education: a bibliometric study and future research agenda

Cogent Arts & Humanities
Blockchain technology (BT) has the potential to transform a number of industries, including education. This bibliometric study examines the state of the field of research in education regarding blockchain, highlighting key developments, influential ...
Iis Kurnia Nuryahati, Mohamad Ibrani Shahrimin Adam Assim, Nia Kurniasih, Harry Nuriman, Mahir Pradana, Alila Pramiyanti   +5 more
doaj   +1 more source

Status and improving countermeasures of information technology education and students' application ability in primary and secondary schools in Qinghai ethnic areas [PDF]

, 2013
Zhanlong Guo
openalex   +1 more source

Using World-Wide-Web technology for pathology education [PDF]

, 1997
In this article, we describe the development of computer-based learning programs for pathology students at Jefferson Medical College. These programs are authored using HTML (HyperText Markup Language), and are available to students on campus and via the ...
Braster, Christopher D, Fenderson, Bruce, Frisby, Anthony J, Murray, Rodney B.   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Engaging the 'Xbox generation of learners' in Higher Education [PDF]

, 2007
The research project identifies examples of technology used to empower learning of Secondary school pupils that could be used to inform students’ engagement in learning with technology in the Higher Education sector.
Ahmed, Jebar, Sheard, Mary
core