Results 41 to 50 of about 150,714 (219)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An exploratory analysis of divergent patterns in reading progression during a tablet-based literacy program

open access: yesFrontiers in Education, 2023
We conducted exploratory research on divergent patterns in reading progression among early grade learners in a low-resourced community to identify key determinants of high versus low reading progress. The sample comprised 30 learners who were purposively
Sarah Bardack   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Current status of responsible use of generative AI in senior high school science teaching in China

open access: yesFrontiers in Education
Generative artificial intelligence (GenAI) rapidly becomes as a powerful education tool globally despite varying opinions about it. Under the ethical threats and safety concerns of GenAI, China set four goals for GenAI education, released specific ...
Sida Lai, Meimiao Chen, Kun Xu
doaj   +1 more source

Defining and modeling of students’ professional thinking development dependence on their training process organization

open access: yesCTE Workshop Proceedings, 2019
The professional thinking issues are analyzed in the research. The authors pointed that the technical thought concepts, images and practical actions are in a complex and dynamic interaction with each other.
Andrey I. Kupin   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Revolutionizing Primary Education Assessment: Opportunities and Challenges in Bandar Lampung's Technology-Driven Landscape

open access: yesTarbawi
This study aims to analyze the opportunities and challenges associated with implementing a technology and information-based educational assessment system in elementary schools in Bandar Lampung.
Nurul Hidayah, Agus Pahrudin, Tri Anjar
doaj   +1 more source

The Technology Imperative in Education [PDF]

open access: yes, 2001
The technological imperative can be an insidious master. It can become the central goal of our endeavors rather than just one way through which goals can be reached. This misdirection can have very real and lasting consequences. For this reason, the basis for action in terms of information systems development and implementation must be kept visible to ...
William T. Bonner, Abhijit Gopal
openaire   +1 more source

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